Blog Archives

The Need for Randomisation in Animal Trials

Randomisation, allocation concealment and blind outcome assessment have been shown to reduce bias in human trials and have been used for over four decades to improve the quality of clinical trials. For animal studies, this has not been thoroughly investigated and

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Reducing waste in preclinical research through better mouse studies

Increasing value and reducing waste in research has to start at the pre-clinical stage, with high quality animal studies and well-characterised mouse models of disease. Steve Perrin provides recommendations for researchers to “make mouse studies work” in a comment in

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Increasing value, reducing waste

Welcome to This website was created to promote the issues raised in a series of articles on research published in early 2014 in the leading medical journal The Lancet.  The website aims to be a platform to share and

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